Identification |
Name: | 4-Thiazolecarboxylicacid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester |
Synonyms: | 2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylicacid methyl ester;2-(1'H-Indole-3'-carbonyl)thiazole-4-carboxylic acid methylester;Methyl 2-(1H-indol-3-ylcarbonyl)-1,3-thiazole-4-carboxylate; |
CAS: | 448906-42-1 |
Molecular Formula: | C14H10N2O3S |
Molecular Weight: | 286.31 |
InChI: | InChI=1/C14H10N2O3S/c1-19-14(18)11-7-20-13(16-11)12(17)9-6-15-10-5-3-2-4-8(9)10/h2-7,15H,1H3 |
Molecular Structure: |
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Properties |
Flash Point: | 268.5°C |
Boiling Point: | 520.4°C at 760 mmHg |
Density: | 1.427g/cm3 |
Refractive index: | 1.688 |
Solubility: | DMSO: 30 mg/mL |
Biological Activity: | Endogenous agonist for the transcription factor aryl hydrocarbon receptor (AHR); K i = 3 nM for binding to murine AHR. Transactivates DRE-containing reporter gene constructs in Hepa1c1c7 cells ~ 5-fold more potently than β -naphthoflavone. Active in vivo . |
Flash Point: | 268.5°C |
Storage Temperature: | 2-8°C |
Safety Data |
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