| Identification | |
| Name: | Bufalin |
| CAS: | 465-21-4 |
| Molecular Formula: | C24H34O4 |
| Molecular Weight: | 386.52 |
| InChI: | InChI=1/C24H34O4/c1-22-10-7-17(25)13-16(22)4-5-20-19(22)8-11-23(2)18(9-12-24(20,23)27)15-3-6-21(26)28-14-15/h3,6,14,16-20,25,27H,4-5,7-13H2,1-2H3/t16-,17+,18-,19?,20?,22+,23-,24+/m1/s1 |
| Molecular Structure: |  |
| Properties | |
| Transport: | UN 3462 |
| Melting Point: | 242 - 243 |
| Density: | 1.226 g/cm3 |
| Stability: | Stable for a year if stored as directed. |
| Refractive index: | 1.593 |
| Solubility: | Insoluble |
| Appearance: | White solid. |
| Packinggroup: | II |
| Storage Temperature: | 2-8°C |
| Usage: | A cardiotonic steroid isolated from bufo species toads that potently inhibits ouabain-sensitive na+,k+-atpase activity. Induces apoptosis in various human cell lines such as leukemia hl60 and u937 cells by altering the expression of apoptosis-related genes. |
| Safety Data | |
| Hazard Symbols |
T+: Very toxic
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