Biological Activity: | Potent and selective 5-HT 2C receptor agonist (pEC 50 values are 9.96, 7.19 and 6.81 for human 5-HT 2C , 5-HT 2B and 5-HT 2A receptors respectively). Displays antipsychotic activity; suppresses condition avoidance responding (CAR) and inhibits PCP and amphetamine-stimulated hyperactivity in rats following subcutaneous administration. |