| Identification | |
| Name: | [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-,(3Z,6R,14aR,14bR)- |
| Synonyms: | Senecionan-11,16-dione,13,19-didehydro-12-hydroxy-; Seneciphylline (6CI,7CI,8CI); Jacodine; NSC 30622;Seneciophylline; Seneciphyllin;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-,[6R-(3Z,6R*,14aR*,14bR*)]-; a-Longilobine |
| CAS: | 480-81-9 |
| Molecular Formula: | C18H23 N O5 |
| Molecular Weight: | 333.38 |
| InChI: | InChI=1/C18H23NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,14-15,22H,2,6-10H2,1,3H3/b12-4-/t14-,15-,18-/m1/s1 |
| Molecular Structure: |  |
| Properties | |
| Transport: | 1544 |
| Melting Point: | 217°C |
| Flash Point: | 303.2°C |
| Boiling Point: | 577.7°C at 760 mmHg |
| Density: | 1.27g/cm3 |
| Stability: | Stable, but reacts with oxygen in the air. Incompatible with alkali, oxidizing agents. Store under inert gas. |
| Refractive index: | 1.581 |
| Water Solubility: | Stability Stable, but reacts with oxygen in the air. Incompatiblewith alkali, oxidizing agents. Store under inert gas. Toxicology Believed to be toxic if swallowed or inhaled. T |
| Solubility: | Sol in chloroform; sparingly sol in ethanol, acetone; slightly sol in water Difficult solubility in ether and ligroin. In water, 1X10+6 mg/L @ 25 deg C /Estimated/ |
| Appearance: | white powder |
| Specification: |
Seneciphylline (CAS NO.480-81-9) is also called 13,19-Didehydro-12-hydroxysenecionan-11,16-dione ; CCRIS 4336 ; HSDB 5188 ; Jacodine ; NCI-C61165 ; NSC 30622 ; Senecionan-11,16-dione, 13,19-didehydro-12-hydroxy- ; Seneciphyllin ; trans-15-Ethylidene-12beta-hydroxy-12alpha-methyl-13-methylenesenec-1-enine ; (1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-, (3Z,6R,14aR,14bR)- 13,19-Didehydro-12-hydroxysenecionan-11,16-dione ; Senecionan-11,16-dione, 13,19-didehydro-12-hydroxy- (9CI) . Seneciphylline (CAS NO.480-81-9) is white powder. It is stable, but reacts with oxygen in the air. Seneciphylline (CAS NO.480-81-9) is incompatible with alkali, oxidizing agents ans store under inert gas. It is insoluble in water. Flash point data are not available for Seneciphylline, but Seneciphylline is probably combustible. |
| Report: |
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 10 ,1976,p. 319.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 10 ,1976,p. 319.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . |
| Packinggroup: | III |
| Flash Point: | 303.2°C |
| Color: | Colorless prisms |
| Safety Data | |
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