2-NITRO-N-[[TRANS-4-[[[(1,2,3,4-TETRAHYDRO-2-NAPHTHALENYL)METHYL]AMINO]METHYL]CYCLOHEXYL]METHYL]BENZENESULFONAMIDE HYDROCHLORIDE (486453-65-0)

Identification
Name:	2-NITRO-N-[[TRANS-4-[[[(1,2,3,4-TETRAHYDRO-2-NAPHTHALENYL)METHYL]AMINO]METHYL]CYCLOHEXYL]METHYL]BENZENESULFONAMIDE HYDROCHLORIDE
Synonyms:	NTNCB HYDROCHLORIDE;2-NITRO-N-[[TRANS-4-[[[(1,2,3,4-TETRAHYDRO-2-NAPHTHALENYL)METHYL]AMINO]METHYL]CYCLOHEXYL]METHYL]BENZENESULFONAMIDE HYDROCHLORIDE;2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride
CAS:	486453-65-0
Molecular Formula:	C25H34ClN3O4S
Molecular Weight:	508.07
InChI:	InChI=1/C25H33N3O4S.ClH/c29-28(30)24-7-3-4-8-25(24)33(31,32)27-18-20-11-9-19(10-12-20)16-26-17-21-13-14-22-5-1-2-6-23(22)15-21;/h1-8,19-21,26-27H,9-18H2;1H/t19-,20-,21?;
Molecular Structure:
Properties
Flash Point:	351.8°C
Boiling Point:	658.2°C at 760 mmHg
Density:	g/cm3
Biological Activity:	Selective, non-peptide competitive NPY Y 5 antagonist. K i values are 8.0 and 16032 nM at human recombinant Y 5 and Y 1 receptors respectively. Potently antagonizes NPY inhibition of forskolin-stimulated cAMP. Displays some affinity for cloned human D 2 and α 2C receptors (K i values are 63 and 100 nM respectively).
Flash Point:	351.8°C
Safety Data