| Identification | |
| Name: | 1H-Indene-3-aceticacid, 5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-, (1Z)- |
| Synonyms: | 1H-Indene-3-aceticacid, 5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-, (Z)-; Sulindacsulfide; Z-Sulindac sulfide; cis-Sulindac sulfide |
| CAS: | 49627-27-2 |
| EINECS: | 256-403-9 |
| Molecular Formula: | C20H17 F O2 S |
| Molecular Weight: | 340.41 |
| InChI: | InChI=1/C20H17FO2S/c1-12-17(9-13-3-6-15(24-2)7-4-13)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9- |
| Molecular Structure: | ![(C20H17FO2S) 1H-Indene-3-aceticacid, 5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-, (Z)-; Sulindacsulfid...](https://img1.guidechem.com/chem/e/dict/50/49627-27-2.jpg) |
| Properties | |
| Flash Point: | 272.1°C |
| Boiling Point: | 526.3°Cat760mmHg |
| Density: | 1.3g/cm3 |
| Specification: | Yellow Solid usageEng:An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120 |
| Flash Point: | 272.1°C |
| Color: | yellow |
| Usage: | An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120 |
| Safety Data | |
| Hazard Symbols |
Xn: Harmful
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