| Identification |
| Name: | 1H-Carbazole-1-carboxamide,6-chloro-2,3,4,9-tetrahydro- |
| Synonyms: | 6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXAMIDE;6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXAMIDE, >95% |
| CAS: | 49843-98-3 |
| Molecular Formula: | C13H13 Cl N2 O |
| Molecular Weight: | 248.71 |
| Molecular Structure: |
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| Properties |
| Density: | 1.389 g/cm3 |
| Biological Activity: | Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC 50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3, HDAC and NADase respectively). Enhances p53 acetylation in response to DNA damaging agents. |
| Safety Data |
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