| Identification | |
| Name: | Dexamethasone |
| Synonyms: | 9-alpha-fluoro-11-beta,17-alpha,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione; 9-alpha-fluoro-16-alpha-methylprednisolone; 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione |
| CAS: | 50-02-2 |
| EINECS: | 200-003-9 |
| Molecular Formula: | C22H29FO5 |
| Molecular Weight: | 392.46 |
| InChI: | InChI=1/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1 |
| Molecular Structure: |  |
| Properties | |
| Transport: | HAZARD |
| Density: | 1.32 g/cm3 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive. |
| Refractive index: | 1.591 |
| Alpha: | 75 o (C=1, DIOXANE) |
| Solubility: | ethanol: 1 mg/mL |
| Appearance: | White crystalline solid |
| Specification: |
?Dexamethasone , its cas register number is 50-02-2. It also can be called 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione .?It is a potent synthetic member of the glucocorticoid class of steroid hormones, and acts as an anti-inflammatory and immunosuppressant. It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. Then you have the ingesting of the product: Wash mouth out with water, and get medical aid immediately. |
| Biological Activity: | Glucocorticoid; anti-inflammatory. Reduces levels of activated NF- κ B in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. |
| Storage Temperature: | 2-8°C |
| Color: | Crystals from ether WHITE TO PRACTICALLY WHITE CRYSTALLINE POWDER |
| Usage: | A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase |
| Safety Data | |
| Hazard Symbols |
Xn:Harmful
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