| Identification | |
| Name: | 4-Pyridinecarboxylicacid, 2-[3-oxo-3-[(phenylmethyl)amino]propyl]hydrazide |
| Synonyms: | Isonicotinicacid, 2-[2-(benzylcarbamoyl)ethyl]hydrazide (6CI,7CI,8CI); 1-[2-(Benzylcarbamoyl)ethyl]-2-isonicotinoylhydrazine;Espril; N1-Beta-Benzylcarbamoyl-ethyl-N2-isonicotinoyl-hydrazine; NSC 124514;Nialamid; Nialamide; Niamid; Niamidal; Niamide; Niaquitil; Niazin; Novazid;Nuredal; Nyezin |
| CAS: | 51-12-7 |
| EINECS: | 200-079-3 |
| Molecular Formula: | C16H18 N4 O2 |
| Molecular Weight: | 298.38 |
| InChI: | InChI=1/C16H18N4O2/c21-15(18-12-13-4-2-1-3-5-13)8-11-19-20-16(22)14-6-9-17-10-7-14/h1-7,9-10,19H,8,11-12H2,(H,18,21)(H,20,22) |
| Molecular Structure: | ![(C16H18N4O2) Isonicotinicacid, 2-[2-(benzylcarbamoyl)ethyl]hydrazide (6CI,7CI,8CI); 1-[2-(Benzylcarbamoyl)ethyl]-...](https://img1.guidechem.com/chem/e/dict/0/51-12-7.jpg) |
| Properties | |
| Transport: | 3249 |
| Melting Point: | 152-154 °C(lit.) |
| Flash Point: | 279.2°C |
| Boiling Point: | 538.1°Cat760mmHg |
| Density: | 1.203g/cm3 |
| Refractive index: | 1.589 |
| Solubility: | Freely soluble in acidic solvents In water, 2,270 mg/L at 25 deg C (est) |
| Specification: |
Nialamide with CAS number of 51-12-7 is also named as 1-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine ; 2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acid ; 2-(2-(Benzylcarbamyl)ethyl)hydrazide isonicotinic acid ; 4-Pyridinecarboxylic acid 2-(3-oxo-3- ; ((phenylmethyl)amino)propyl)hydrazide ; 5-22-02-00251 (Beilstein Handbook Reference) ; BEIH ; BRN 0492941 ; CCRIS 3512 ; Delmoneurina ; Delmoneurinaesprilisalizina ; EINECS 200-079-3 ; Espril ; Isalizina ; Isonicotinic acid 2-((2-benzylcarbamoyl)ethyl)hydrazide ; Isonicotinic acid, 2-(2-(benzylcarbamoyl)ethyl)hydrazide ; Mygal ; N(sup 1)-beta-Benzylcarbamoylethyl-N(sup 2)-isonicotinoylhydrazine ; N(sup1)-beta-Benzylcarbamoylethyl-N(sup2)-isonicotinoylhydrazine ; N-(2-(Benzylcarbamyl)ethylamino)isonicotinamide ; N-Benzyl-beta-(isonicotinoylhydrazine)propionamide ; N-Benzyl-beta-(isonicotinylhydrazino)propionamide ; N-Isonicotinoyl-N'(beta-N-benzylcarboxamidoethyl)hydrazine ; NSC 124514 ; Nialamid ; Nialamida ; Nialamida [INN-Spanish] ; Nialamide ; Nialamidum ; Nialamidum [INN-Latin] ; Niamid ; Niamidal ; Niamide ; Niaquitil ; Niazin ; Novazid ; Nuredal ; Nyazin ; P 1133 ; Psicodisten ; Surgex ; UNII-T2Q0RYM725 . Nialamide is sometimes used in the treatment of trigeminal neuralgia. It has also been studied for alcoholism, dermatomally distributed vitiligo, irregular menstruation, angina, cerebrovascular disorders, and the prevention of streptomycin-induced deafness.Side effects of nialamide include euphoria, psychomotor agitation, insomnia, anxiety, headache, vertigo, tremor, hyperreflexia, manic state, arterial hypotension, orthostatic hypotension, arterial hypertension, palpitations, hyperhidrosis, dry mouth, nausea, vomiting, epigastric pain, constipation, vision problems, retrobulbar optic neuritis, polyneuritis, weight gain, acute cardiac insufficiency, tachycardia, peripheral neuropathy, jaundice, hepatomegaly, hyperbilirubinemia, urinary retention, elevated transaminases, hepatitis, hepatocellular insufficiency, cutaneous eruption, impotence, and delayed ejaculation. |
| Report: |
EPA Genetic Toxicology Program. |
| Packinggroup: | III |
| Flash Point: | 279.2°C |
| Storage Temperature: | −20°C |
| Color: | White crystalline powder |
| Safety Data | |
| Hazard Symbols | |
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