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Fluorouracil (5-Fluorouracil) (51-21-8)

Identification
Name:Fluorouracil (5-Fluorouracil)
Synonyms:Ro-2-9757;Phtoruracil;Ulup;2,4(1H,3H)-Pyrimidinedione,5-fluoro-;Phthoruracil;Uracil, 5-fluoro-;5-Fluoro-2,4(1H, 3H)-pyrimidinedione;2,4 (1H, 3H)-Pyrimidinedione, 5-fluoro-;5-Fluoro-2,4(1H,3H)-pyrimidinedione;Fluoroplex;5-Fluoracyl;Efudex;Effluderm (free base);U 8953;Adrucil;Efurix;5-Ftouracyl;2,4(1H,3H)-pyrimidinedione, 5-fluoro-;5-Fluoropyrimidine-2,4-dione;U-8953;Arumel;Kecimeton;Fluoroblastin;2,4-Dioxo-5-fluoropryimidine;Fluro Uracil;Uracil, 5-fluoro- (VAN 8CI);Fluracil;Efudix;Ro 2-9757;5-fluoro-1H-pyrimidine-2,4-dione;5-FU (TN);Carzonal;Fluracilum;5-FU;5FU;5-Fluoro-2,4-pyrimidinedione;Fluril;FU;Fluri;Fluorouracil (JP14/USP);Adrucil (TN);Queroplex;Timazin;Fludrocortisone;5-FLUORACIL (GERMAN);5-FLUORO-2,4(1H,3H)-PYRIMIDINEDI-ONE;5-FLUORPROPYRIMIDINE-2,4-DIONE;5-FLUORO-2,4-PYRIMI-DINEDIONE;5-FLUORURACIL (GERMAN);NSC-19893;5-Fluoro Uracil;5-Fluoropyrimidine;Carmofur 5-Fluoro Uracil;5-Fluorouracl;5-Fluorouracilum;
CAS:51-21-8
EINECS: 200-085-6
Molecular Formula: C4H3FN2O2
Molecular Weight: 130.0772
InChI: InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
Molecular Structure: (C4H3FN2O2) Ro-2-9757;Phtoruracil;Ulup;2,4(1H,3H)-Pyrimidinedione,5-fluoro-;Phthoruracil;Uracil, 5-fluoro-;5-Flu...
Properties
Transport:UN 2811 6.1/PG 3
Density:1.53 g/cm3
Stability:Stable. Light sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases.
Refractive index:1.542
Solubility:insoluble in water
Appearance:white to nearly white crystalline powder
Specification:

?Fluorouracil , its cas register number is 51-21-8. It also can be called?2,4(1H,3H)-Pyrimidinedione, 5-fluoro- ; 2,4-Dioxo-5-fluoropyrimidine ; 5-FU ; 5-Faracil ; 5-Fluor-2,4(1H,3H)-pyrimidindion ; 5-Fluor-2,4-dihydroxypyrimidin .It is a?white to nearly white crystalline powder and?insoluble in water.

Packinggroup: III
HS Code: 29335995
Biological Activity: Anticancer agent. Metabolized to form fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine (FUTP). FdUMP inhibits thymidylate reductase causing a reduction in dTMP synthesis. FUTP and FdUTP are misincorporated into RNA and DNA respectively.
Storage Temperature: Store at 0-5
Sensitive: Air Sensitive
Color: white
Usage:

A potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis

Safety Data
Hazard Symbols Xn:Harmful