| Identification |
| Name: | 1,3,8-Triazaspiro[4.5]decan-4-one,8-[3-(4-fluorophenoxy)propyl]-1-phenyl- |
| Synonyms: | 1,3,8-Triazaspiro[4.5]decan-4-one,8-[3-(p-fluorophenoxy)propyl]-1-phenyl- (7CI,8CI);8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one; AMI193; Spiramide; Spiramide (pharmaceutical) |
| CAS: | 510-74-7 |
| Molecular Formula: | C22H26 F N3 O2 |
| Molecular Weight: | 383.4591 |
| InChI: | InChI=1/C22H26FN3O2/c23-18-7-9-20(10-8-18)28-16-4-13-25-14-11-22(12-15-25)21(27)24-17-26(22)19-5-2-1-3-6-19/h1-3,5-10H,4,11-17H2,(H,24,27) |
| Molecular Structure: |
![(C22H26FN3O2) 1,3,8-Triazaspiro[4.5]decan-4-one,8-[3-(p-fluorophenoxy)propyl]-1-phenyl- (7CI,8CI);8-[3-(4-Fluoroph...](https://img1.guidechem.com/chem/e/dict/31/510-74-7.jpg) |
| Properties |
| Flash Point: | 322.2 ºC |
| Boiling Point: | 609.1 ºC at 760 mmHg |
| Density: | 1.26 g/cm3 |
| Refractive index: | 1.621 |
| Biological Activity: | Selective 5-HT antagonist, which binds to 5-HT 2 sites as potently as spiperone but has lower affinity for 5-HT 2C receptors. Also a high affinity D 2 receptor antagonist (K i = 3 nM). Lacks the disruptive effect of spiperone on animal behavior. |
| Flash Point: | 322.2 ºC |
| Storage Temperature: | Store at RT |
| Safety Data |
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