Identification |
Name: | Guanosine, 8-bromo-,cyclic 3',5'-(hydrogen phosphate), monosodium salt (9CI) |
Synonyms: | 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin,guanosine deriv.; 8-Bromo-cGMP monosodium salt; 8-Bromoguanosine cyclic3',5'-monophosphate sodium salt |
CAS: | 51116-01-9 |
EINECS: | 256-993-8 |
Molecular Formula: | C10H11 Br N5 O7 P . Na |
Molecular Weight: | 424.1014 |
InChI: | InChI=1/C10H11BrN5O7P.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5;/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18);/q;+1/p-1/t2-,4-,5-,8-;/m1./s1 |
Molecular Structure: |
|
Properties |
Density: | 2.96 g/cm3 |
Biological Activity: | Membrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1 α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro . |
Storage Temperature: | −20°C |
Safety Data |
|
|