L-Glutamic acid,N-[3,5-dichloro-4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (528-74-5)

Identification
Name:	L-Glutamic acid,N-[3,5-dichloro-4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
Synonyms:	Glutamicacid, N-[3,5-dichloro-4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-(6CI,7CI); Glutamic acid,N-[3,5-dichloro-4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(8CI); 3,5-Dichloromethotrexate; 3',5'-Dichloroamethopterin;3',5'-Dichloromethotrexate; Dichloromethotrexate; Methotrexate, dichloro-; NSC145883; NSC 29630
CAS:	528-74-5
Molecular Formula:	C20H20 Cl2 N8 O5
Molecular Weight:	523.38
InChI:	InChI=1/C20H20Cl2N8O5/c1-30(7-9-6-25-17-14(26-9)16(23)28-20(24)29-17)15-10(21)4-8(5-11(15)22)18(33)27-12(19(34)35)2-3-13(31)32/h4-6,12H,2-3,7H2,1H3,(H,27,33)(H,31,32)(H,34,35)(H4,23,24,25,28,29)
Molecular Structure:
Properties
Density:	1.637g/cm³
Refractive index:	1.739
Specification:	3',5'-Dichloromethotrexate (CAS NO.528-74-5) is a light yellow or yellow powder.It insoluble in water.When heated to decomposition,it emits toxic fumes.It is probably combustible.
Report:	NCI Carcinogenesis Studies (ipr): Equivocal Evidence: rat; No Evidence: mouse CANCAR Cancer. 40 (1977),1935. .
Safety Data