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2(1H)-Pyridinone,5-methyl-1-phenyl- (53179-13-8)

Identification
Name:2(1H)-Pyridinone,5-methyl-1-phenyl-
Synonyms:5-Methyl-1-phenyl-1H-pyridin-2-one;5-Methyl-1-phenyl-2(1H)-pyridinone;5-Methyl-1-phenyl-2(1H)-pyridone;AMR 69;Deskar;Pirespa;Pirfenidone;
CAS:53179-13-8
Molecular Formula: C12H11NO
Molecular Weight: 185.22184
InChI: InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
Molecular Structure: (C12H11NO) 5-Methyl-1-phenyl-1H-pyridin-2-one;5-Methyl-1-phenyl-2(1H)-pyridinone;5-Methyl-1-phenyl-2(1H)-pyrido...
Properties
Melting Point: 96-97ºC
Flash Point: 152.7 ºC
Boiling Point: 329.1ºC at 760 mmHg
Density:1.137 g/cm3
Refractive index:1.592
Appearance:Off-White Solid
Specification:
Off-White Solid
usageEng:Pirfenidone has demonstrated activity in multiple fibrotic conditions, including those of the lung, kidney and liver
Safety Statements:36
36:Wear suitable protective clothing
Biological Activity: Antifibrotic agent, effective in models of pulmonary and lung fibrosis. Inhibits collagen production and fibroblast proliferation. Regulates cytokine levels following oral administration in vivo . Potent scavenger of free radicals and inhibitor of lipid peroxidation.
Flash Point: 152.7 ºC
Storage Temperature: Store at RT
Usage:

 2(1H)-Pyridinone,5-methyl-1-phenyl- (CAS NO.53179-13-8) is used in multiple fibrotic conditions, including those of the lung, kidney and liver.

Safety Data
Hazard Symbols Xn:Harmful