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2-Propanamine,1-(2,6-dimethylphenoxy)-, hydrochloride (1:1) (5370-01-4)

Identification
Name:2-Propanamine,1-(2,6-dimethylphenoxy)-, hydrochloride (1:1)
Synonyms:2-Propanamine,1-(2,6-dimethylphenoxy)-, hydrochloride (9CI);Ethylamine, 1-methyl-2-(2,6-xylyloxy)-,hydrochloride (7CI,8CI);Katen;Ko 1173;Ko 1173Cl;Mexiletinehydrochloride;Mexilitene;Mexitil;Ritalmex;
CAS:5370-01-4
EINECS: 226-362-1
Molecular Formula: C11H17NO.HCl
Molecular Weight: 179.25878
InChI: InChI=1S/C11H17NO/c1-8-5-4-6-9(2)11(8)13-7-10(3)12/h4-6,10H,7,12H2,1-3H3
Molecular Structure: (C11H17NO.HCl) 2-Propanamine,1-(2,6-dimethylphenoxy)-, hydrochloride (9CI);Ethylamine, 1-methyl-2-(2,6-xylyloxy)-,h...
Properties
Density:0.979 g/cm3
Water Solubility:ethanol: 50 mg/mL in water
Solubility:ethanol: 50 mg/mL in water
Appearance:white to off-white solid
Specification:

 Mexiletine hydrochloride (5370-01-4) belongs to the Class IB anti-arrhythmic group of medicines. It is used to treat arrhythmias within the heart - or seriously irregular heartbeats. It slows nerve impulses in the heart and makes the heart tissue less sensitive.The common side effects are  Dizziness, heartburn, nausea, nervousness, trembling, unsteadiness and so on. It is available in injection and capsule form. and it also may be of use in patients experiencing refractory pain.and is also effective for treating muscle stiffness resulting from myotonia congenita .

Biological Activity: Use-dependent sodium channel blocker (IC 50 values are 75.3 and 23.6 μ M for tonic and use-dependent block respectively). Class Ib antiarrhythmic, neuroprotective and antimyotonic agent.
Storage Temperature: 2-8°C
Color: white
Usage:Antiarrhythmic (class IB)
Safety Data
Hazard Symbols Xn:Harmful