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Benzoicacid, 2-[[3-(3,4-dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]- (53902-12-8)

Identification
Name:Benzoicacid, 2-[[3-(3,4-dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]-
Synonyms:Anthranilic acid, N-(3,4-dimethoxycinnamoyl)-;N-(3,4-Dimethoxycinnamoyl)anthranilic acid;MK 341;
CAS:53902-12-8
Molecular Formula: C18H17NO5
Molecular Weight: 327.33128
InChI: InChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+
Molecular Structure: (C18H17NO5) Anthranilic acid, N-(3,4-dimethoxycinnamoyl)-;N-(3,4-Dimethoxycinnamoyl)anthranilic acid;MK 341;
Properties
Density:1.299 g/cm3
Refractive index:1.647
Water Solubility:Soluble to 100 mM in DMSO
Solubility:18 mg/mL in DMSO
Appearance:white with light yellow crystalline powder
Biological Activity: Antiallergic via inhibition of chemical mediator release from mast cells. Most recently shown to be an effective inhibitor of angiogenesis. Demonstrated to antagonize the effects of angiotensin II on human arteries, possibly by an interaction at the level of the AT 1 receptor.
Usage:An antiallergic drug.
Safety Data
Hazard Symbols Xn:Harmful
 

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