| Identification | |
| Name: | Con-5-enin-3-amine,N,N-dimethyl-, (3b)- |
| Synonyms: | Con-5-enine,3b-(dimethylamino)- (8CI);Conessine (6CI); Conkurchine, N,18-dihydrotrimethyl- (7CI);1H-Naphth[2',1':4,5]indeno[1,7a-c]pyrrole, con-5-enin-3-amine deriv.;(+)-Conessine; Conessin; NSC 119994; Neriine;N',18-Dihydro-N,N,N'-trimethylconkurchine; Roquessine; Wrightine |
| CAS: | 546-06-5 |
| EINECS: | 208-897-2 |
| Molecular Formula: | C24H40N2 |
| Molecular Weight: | 356.59 |
| InChI: | InChI=1/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/t16-,18-,19?,20+,21?,22?,23-,24-/m0/s1 |
| Molecular Structure: |  |
| Properties | |
| Melting Point: | 126-127°C |
| Flash Point: | 199.6°C |
| Boiling Point: | 450.4°C at 760 mmHg |
| Density: | 1.05g/cm3 |
| Refractive index: | 1.564 |
| Specification: | usageEng:Conessine is a steroidal dibasic alkaloid with a rigid steroid-based skeleton. Conessine is a potent and selective histamine H3 receptor antagonist. |
| Biological Activity: | Potent and selective histamine H 3 receptor antagonist (pK i values are 7.61 and 8.27 at rat and human H 3 receptors respectively). A steroidal alkaloid that displays in vitro antiplasmodial activity (IC 50 = 1.04 μ M). Also has high affinity for α 2C adrenoceptors (pK i = 7.98). |
| Flash Point: | 199.6°C |
| Storage Temperature: | Store at RT |
| Usage: | Conessine is a steroidal dibasic alkaloid with a rigid steroid-based skeleton. Conessine is a potent and selective histamine H3 receptor antagonist. |
| Safety Data | |
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