| Identification | |
| Name: | 4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime |
| Synonyms: | 4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime;AP-18 |
| CAS: | 55224-94-7 |
| Molecular Formula: | C11H12ClNO |
| Molecular Weight: | 0 |
| Molecular Structure: |  |
| Properties | |
| Biological Activity: | Reversible TRPA1 channel blocker (IC 50 values are 3.1 and 4.5 μ M at human and mouse TRPA1 respectively). Blocks cinnameldehyde-induced but not capsaicin-induced nociception and reverses mechanical hyperalgesia in vivo . Also blocks TRPA1 pore dilation (IC 50 = 10.3 μM for the inhibition of Yo-Pro uptake). |
| Storage Temperature: | 2-8°C |
| Safety Data | |
 |
|
