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1-Azabicyclo[2.2.2]octan-3-one,2,2-bis(hydroxymethyl)- (5608-24-2)

Identification
Name:1-Azabicyclo[2.2.2]octan-3-one,2,2-bis(hydroxymethyl)-
Synonyms:3-Quinuclidinone,2,2-bis(hydroxymethyl)- (7CI,8CI); NSC 281668; PRIMA 1
CAS:5608-24-2
Molecular Formula: C9H15 N O3
Molecular Weight: 185.22
InChI: InChI=1/C9H15NO3/c11-5-9(6-12)8(13)7-1-3-10(9)4-2-7/h7,11-12H,1-6H2
Molecular Structure: (C9H15NO3) 3-Quinuclidinone,2,2-bis(hydroxymethyl)- (7CI,8CI); NSC 281668; PRIMA 1
Properties
Flash Point: 167.7°C
Boiling Point: 353.7°Cat760mmHg
Density:1.32g/cm3
Refractive index:1.581
Biological Activity: Selectively restores mutant p53 activity in tumor cells via activation of Bax and PUMA. Induces apoptosis and inhibits growth of human tumors with mutant p53.
Flash Point: 167.7°C
Safety Data