[1,4]Diazepino[6,7,1-jk]carbazole,4,5,6,7,9,10,11,12-octahydro- (57756-45-3)

Identification
Name:	[1,4]Diazepino[6,7,1-jk]carbazole,4,5,6,7,9,10,11,12-octahydro-
Synonyms:	[1,4]Diazepino[6,7,1-jk]carbazole,1,2,3,4,8,9,10,11-octahydro- (9CI); WAY 629
CAS:	57756-45-3
Molecular Formula:	C15H18 N2
Molecular Weight:	262.78
InChI:	InChI=1S/C15H18N2.ClH/c1-2-7-14-12(5-1)13-6-3-4-11-10-16-8-9-17(14)15(11)13;/h3-4,6,16H,1-2,5,7-10H2;1H
Molecular Structure:
Properties
Biological Activity:	Selective 5-HT 2C agonist. K i values are 56, 2350, 1575 and 815 nM for human recombinant 5-HT 2C , 5-HT 2A , 5-HT 6 and 5-HT 7 receptors respectively. Stimulates intracellular Ca 2+ mobilization in CHO cells expressing human 5-HT 2C receptors (EC 50 = 72 nM). Reduces food intake in rats.
Safety Data

1/C12H9NO/c14-9-11-3-1-2-4-12(11)10-5-7-13-8-6-10/h1-9
1/C9H7NO2/c1-10-7-5-3-2-4-6(7)8(11)9(10)12/h2-5H,1H
Spiro[furan-3(2H),7'(4'H)-naphtho[2,1-g]quinoline]-4',5,6',10'(4H,6'aH,7'aH)-tetrone,1',4'a,5',8',9',11',12'a,12'b-octahydro-2',5',7'a,12'a-tetramethyl-11'-[[(2R,4R)-tetrahydro-4-methyl-5-oxo-2-furanyl]methyl]-,(3S,4'aS,5'S,6'aR,7'aR,12'aS,12'bS)-rel-(+)- (9CI)
1/C7H10N4O/c1-2-9-10-7(8-1)11-3-5-12-6-4-11/h1-2H,3-6H
1/C11H10O2/c1-9(12)3-4-10-5-7-11(13-2)8-6-10/h5-8H,1-2H
1/C9H12N2O2/c1-5-7-6(11-13-5)4-9(2,3)10-8(7)12/h4H2,1-3H3,(H,10,12
1/C12H17NO2/c14-11-4-2-1-3-9(11)7-10-8-12(5-6-12)15-13-10/h9H,1-8H
1/C9H6N2S/c1-7-2-3-9(12-7)4-8(5-10)6-11/h2-4H,1H
1/C12H19N/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9H,13H2,1-4H
1/C10H8N2/c1-2-6-12-10(3-1)9-4-7-11-8-5-9/h1-8
1/C8H9NO3/c1-6-3-4-8(12-2)7(5-6)9(10)11/h3-5H,1-2H
1/C7H5N3O2/c8-10-9-6-4-2-1-3-5(6)7(11)12/h1-4H,(H,11,12
1/C8H9ClO2S/c1-11-6-4-3-5(9)7(10)8(6)12-2/h3-4,10H,1-2H
1/C9H11BrO2/c1-6-4-9(12-3)7(10)5-8(6)11-2/h4-5H,1-3H
1-(4 4 5 5 6 6 7 7 8 8 9 9 10 10 11 11 1
4-(4 4 5 5 6 6 7 7 8 8 9 9 10 10 11 11 1
1/C8H18B2O2/c1-11-9-5-3-7-10(12-2)8-4-6-9/h3-8H2,1-2H
1/C8H9NO3/c1-6-2-3-7(5-10)4-8(6)9(11)12/h2-4,10H,5H2,1H
1/C6H9N5O2/c1-8-6-9-4(7)3(10-13)5(12)11(6)2/h7H2,1-2H3,(H,8,9
1/C7H3Cl2FO2/c8-4-2-5(9)6(10)1-3(4)7(11)12/h1-2H,(H,11,12