| Identification | |
| Name: | Imidazo[2,1-b]quinazolin-2(3H)-one,6,7-dichloro-1,5-dihydro-, hydrochloride (1:1) |
| Synonyms: | Imidazo[2,1-b]quinazolin-2(3H)-one,6,7-dichloro-1,5-dihydro-, monohydrochloride (9CI);6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one Hydrochloride;Agrelin;Agrylin;BL 4162A;BMY 26538-01; |
| CAS: | 58579-51-4 |
| Molecular Formula: | C10H8Cl3N3O |
| Molecular Weight: | 292.54902 |
| InChI: | InChI=1S/C10H7Cl2N3O.ClH/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7;/h1-2H,3-4H2,(H,13,14,16);1H |
| Molecular Structure: | ![(C10H8Cl3N3O) Imidazo[2,1-b]quinazolin-2(3H)-one,6,7-dichloro-1,5-dihydro-, monohydrochloride (9CI);6,7-Dichloro-1...](https://img.guidechem.com/casimg/58579-51-4.gif) |
| Properties | |
| Melting Point: | >280ºC |
| Flash Point: | 181.5 ºC |
| Boiling Point: | 376.5 ºC at 760 mmHg |
| Density: | 1.77g/cm3 |
| Water Solubility: | Soluble to 10 mM in DMSO,soluble in water |
| Solubility: | Soluble to 10 mM in DMSO,soluble in water |
| Appearance: | Off-white powder |
| Specification: |
Imidazo[2,1-b]quinazolin-2(3H)-one,6,7-dichloro-1,5-dihydro-, hydrochloride (1:1) (CAS NO.58579-51-4), its Synonyms are 6,7-Dichloro-1,5-dihydroimidazo(2,1-b)-quinazolin-2(3H)-one monohydrochloride ; Agrelin ; Agrylin ; Anagrelid hydrochlorid ; Anagrelide HCl ; Anagrelide hydrochloride ; Imidazo(2,1-b)quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-, monohydrochloride . |
| Biological Activity: | Potent type III phosphodiesterase (PDE3) inhibitor (IC 50 = 36 nM). Inhibits platelet aggregation and produces potent thrombocytopenic effects via inhibition of megakaryocyte maturation. |
| Flash Point: | 181.5 ºC |
| Usage: |
Imidazo[2,1-b]quinazolin-2(3H)-one,6,7-dichloro-1,5-dihydro-, hydrochloride (1:1) (CAS NO.58579-51-4) is used as an antithrombocythemic. |
| Safety Data | |
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