Specification: |
The tyramine monochloride , with the CAS register number 60-19-5, has other names as 2-(3-indolyl)ethylamine hydrochloride ; 3-(2-aminoethyl)indole hcl;tryptamine hcl ; tryptamine hydrochloride ; timtec-bb sbb000359 ; 4-(2-aminoethyl)-phenohydrochloride ; p-(2-aminoethyl)-phenomonohydrochloride ; phenol,4-(2-aminoethyl)-,hydrochloride .
The characteristics of this chemical are as the following: (1)#H bond acceptors: 2 ; (2)#H bond donors: 3 ; (3)#Freely Rotating Bonds: 4 ; (4)Polar Surface Area: 12.47 ; (5)Index of Refraction: 1.577 ; (6)Molar Refractivity: 41.21 cm3 ; (7)Molar Volume: 124.3 cm3 ; (8)Polarizability: 16.34 ×10-24 cm3 ; (9)Surface Tension: 48.3 dyne/cm ; (10)Density: 1.103 g/cm3 ; (11)Flash Point: 119.2 °C ; (12)Enthalpy of Vaporization: 58.99 kJ/mol ; (13)Boiling Point: 325.2 °C at 760 mmHg ; (14)Vapour Pressure: 0.000123 mmHg at 25°C .
It is a off-white to light yellow powder and it is hygroscopic. Being a kind of irritant chemical to eyes, respiratory system and skin, it may cause inflammation to the skin or other mucous membranes. So while dealing with this chemcial, we need to be very careful. Wear suitable protective clothing and if in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, avoid contact with skin and eyes and do not breathe dust. If you need more safety information, you could refer to the WGK Germany 3. When store it, you should keep it at RT. What's more, its product categories are including anilines, aromatic amines and nitro compounds;amines;aromatics.
In addition, you could refer to the following data information to get the molecular structure:
SMILES:Oc1ccc(cc1)CCN
InChI:InChI=1/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2
InChIKey:DZGWFCGJZKJUFP-UHFFFAOYAB
Below are the toxicity information of this kind of chemical:
Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
guinea pig |
LDLo |
subcutaneous |
1044mg/kg (1044mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Journal of Pharmacology and Experimental Therapeutics. Vol. 47, Pg. 339, 1933. |
mouse |
LD50 |
intraperitoneal |
710mg/kg (710mg/kg) |
|
Toxicology and Applied Pharmacology. Vol. 28, Pg. 227, 1974.
|
mouse |
LD50 |
intravenous |
208mg/kg (208mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
European Journal of Pharmacology. Vol. 9, Pg. 289, 1970.
|
mouse |
LDLo |
unreported |
2750mg/kg (2750mg/kg) |
|
Journal of Pharmacology and Experimental Therapeutics. Vol. 8, Pg. 126, 1916 |
|