| Identification | |
| Name: | Teicoplanin A2 |
| Synonyms: | Teicoplanin A 2 (9CI);Teichomycin A2; |
| CAS: | 61036-64-4 |
| Molecular Formula: | C78H78Cl2N9O32R |
| Molecular Weight: | 1709.39 |
| InChI: | InChI=1/C90H99Cl2N9O34/c1-5-6-7-8-9-10-11-12-60(110)95-69-76(116)73(113)58(32-103)132-89(69)135-80-55-27-41-28-56(80)128-51-20-16-39(23-46(51)92)79(134-88-68(94-35(3)105)75(115)72(112)57(31-102)131-88)70-86(124)99-66(87(125)126-4)44-29-42(106)30-54(130-90-78(118)77(117)74(114)59(33-104)133-90)61(44)43-21-37(14-17-47(43)107)63(82(120)101-70)96-84(122)65(41)97-83(121)64-40-24-49(109)34(2)52(26-40)129-53-25-36(13-18-48(53)108)62(93)81(119)100-67(85(123)98-64)71(111)38-15-19-50(127-55)45(91)22-38/h9-10,13-30,57-59,62-79,88-90,102-104,106-109,111-118H,5-8,11-12,31-33,93H2,1-4H3,(H,94,105)(H,95,110)(H,96,122)(H,97,121)(H,98,123)(H,99,124)(H,100,119)(H,101,120)/b10-9+ |
| Molecular Structure: |  |
| Properties | |
| Melting Point: | 260 ºC |
| Solubility: | Soluble in DMF, dimethylsulfoxide and aqueous solution with pH of 7.0, partly soluble in methanol or ethanol, insoluble in dilute inorganic acid and the polar organic solvents |
| Appearance: | Amorphous powder |
| Specification: |
Teicoplanin A2 (61036-64-4) is evaluated in vitro against clinical isolates, and its activity was compared with that of other antibiotics. This compound was very active against all organisms tested; its activity was comparable to that of vancomycin, and it was superior to several other antibiotics when tested against gram-positive cocci. Because of its in vitro activity, it deserves clinical evaluation. |
| Safety Data | |
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