Identification |
Name: | 1H-Pyrrole-2-carboxamide,4-[[2-[(aminoiminomethyl)amino]acetyl]amino]-N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-,hydrochloride (1:?) |
Synonyms: | 1H-Pyrrole-2-carboxamide,4-[[[(aminoiminomethyl)amino]acetyl]amino]-N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-,hydrochloride (9CI); Netropsin hydrochloride (7CI) |
CAS: | 63770-20-7 |
Molecular Formula: | C18H26 N10 O3 . x Cl H |
Molecular Weight: | 467.00 |
InChI: | InChI=1/C18H26N10O3.ClH/c1-27-9-11(6-12(27)16(30)23-4-3-15(20)29)26-17(31)13-5-10(8-28(13)2)25-14(19)7-24-18(21)22;/h5-6,8-9H,3-4,7H2,1-2H3,(H2,19,25)(H2,20,29)(H,23,30)(H,26,31)(H4,21,22,24);1H |
Molecular Structure: |
![(C18H26N10O3.xClH) 1H-Pyrrole-2-carboxamide,4-[[[(aminoiminomethyl)amino]acetyl]amino]-N-[5-[[(3-amino-3-iminopropyl)am...](https://img1.guidechem.com/chem/e/dict/36/63770-20-7.jpg) |
Properties |
Transport: | UN 2811 6.1/PG 3 |
Flash Point: | 391.8°C |
Boiling Point: | 724.2°C at 760 mmHg |
Specification: |
Netropsin Hydrochloride (CAS NO.63770-20-7) is a faint yellow powder. Unusual n-methylpyrrole-containing oligopeptide that binds to AT-rich sequences of dsDNA, especially in the minor groove. Thus, it protects such regions from DNase I and other endonucleases, and also inhibits topoisomerases. Netropsin Hydrochloride disrupts the cell cycle, prolonging G and arresting in G.
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Flash Point: | 391.8°C |
Storage Temperature: | −20°C |
Color: | faint yellow |
Safety Data |
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