Identification |
Name: | artemisinin |
Synonyms: | (+)-Arteannuin; Qinghaosu; [3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-one; Artemisinine |
CAS: | 63968-64-9 |
Molecular Formula: | C15H22O5 |
Molecular Weight: | 282.33 |
InChI: | InChI=1/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1 |
Molecular Structure: |
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Properties |
Density: | 1.24 g/cm3 |
Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides. May absorb, and react with, carbon dioxide from the air. |
Alpha: | 76 o (C=0.5,MEOH) |
Solubility: | Insoluble |
Appearance: | Crystalline Solid |
Specification: |
?Artemisinin (CAS NO.63968-64-9) is also called (+)-Arteannuin ; Qinghaosu? and [3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-one? .
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HS Code: | 29322985 |
Biological Activity: | Antimalarial agent; interacts with heme to produce carbon-centred free radicals, causes protein alkylation and damages parasite microorganelles and membranes. Also selectively inhibits the P-type ATPase (PfATP6) of Plasmodium falciparum (K i ~ 150 nM). Displays antiangiogenic effects in mouse embryonic stem cell-derived embryoid bodies. |
Storage Temperature: | Store in a cool, dry place. Store in a tightly closed container. |
Usage: | Active antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial |
Safety Data |
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