2,4(1H,3H)-Pyrimidinedione,6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl-,hydrochloride (1:1) (64887-14-5)

Identification
Name:	2,4(1H,3H)-Pyrimidinedione,6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl-,hydrochloride (1:1)
Synonyms:	2,4(1H,3H)-Pyrimidinedione,6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl-,monohydrochloride (9CI);Urapidil hydrochloride;
CAS:	64887-14-5
Molecular Formula:	C₂₀H₂₉N₅O₃^.HCl
Molecular Weight:	423.9369
InChI:	InChI=1S/C20H29N5O3.ClH/c1-22-18(15-19(26)23(2)20(22)27)21-9-6-10-24-11-13-25(14-12-24)16-7-4-5-8-17(16)28-3;/h4-5,7-8,15,21H,6,9-14H2,1-3H3;1H
Molecular Structure:
Properties
Melting Point:	156-1580C
Water Solubility:	H2O: soluble
Solubility:	H2O: soluble
Appearance:	white or off-white crystalline powder
Specification:	Urapidil hydrochloride (CAS NO.64887-14-5) is also named as Ebrantil ; Urapidil HCl ; 6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione hydrochloride ; 6[[3-[4-(o-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil hydrochloride ; 2,4(1H,3H)-Pyrimidinedione, 6-((3-(4-(2-methoxyphenyl)-1- piperazinyl)propyl)amino)-1,3-dimethyl-, monohydrochloride . Urapidil hydrochloride (CAS NO.64887-14-5) is white to off-white crystalline powder.
Biological Activity:	α 1 -adrenoceptor antagonist and 5-HT 1A receptor agonist (pIC 50 values are 6.13 and 6.4 respectively). Clinically used hypotensive agent.
Storage Temperature:	Desiccate at RT
Color:	white
Usage:	a1-Adrenergic antagonist; derivative of Uracil. Antihypertensive
Safety Data
Hazard Symbols	Xn:Harmful