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Nicotine ditartrate (65-31-6)

Identification
Name:Nicotine ditartrate
Synonyms:3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate
CAS:65-31-6
EINECS: 200-607-2
Molecular Formula: C10H14N2.2(C4H6O6)
Molecular Weight: 462.46
InChI: InChI=1/C10H14N2.C4H6O6/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;5-1(3(7)8)2(6)4(9)10/h2,4,6,8,10H,3,5,7H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t10-;/m0./s1
Molecular Structure: (C10H14N2.2(C4H6O6)) 3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate
Properties
Transport:UN 1659 6.1/PG 2
Flash Point: 101.7°C
Stability:Stable under normal temperatures and pressures.
Water Solubility:1000000 mg l-1 (e)
Solubility:1000000mgl-1(e)
Appearance:A reddish white crystalline solid.
Specification:

Appearance: a reddish white crystalline solid.
Solubility in water: very Soluble.
First Aid Measures:
Ingestion: get medical aid. Do not induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation: remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Skin: get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes:  flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. 
Handling and Storage:
Storage: store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.
Handling: wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. 

Packinggroup: II
Biological Activity: Nicotinic acetylcholine receptor (nAChR) agonist (K i values are 1, > 1000, 4000 and 7130 nM at α 4 β 2, α 1 β 1 δ γ , rat α 7 and human α 7 respectively). Exhibits vasoconstrictive, hypertensive and prothrombotic activity in vivo .
Flash Point: 101.7°C
Storage Temperature: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.
Color: white to off-white
Usage:Used in a medicine as a drug which counteracts the effect of tetanus and strychnine poisoning.
Safety Data
 

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