Identification |
Name: | 1,3-Cyclohexanedione,5,5-dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1-oxo-1H-xanthen-9-yl)- |
Synonyms: | 1,3-Cyclohexanedione,5,5-dimethyl-2-(1,2,3,4-tetrahydro-3,3-dimethyl-1-oxoxanthen-9-yl)- (7CI);9-(4,4-Dimethyl-2,6-dioxocyclohexyl)-1,2,3,4-tetrahydro-3,3-dimethyl-1-xanthenone;L 152804 |
CAS: | 6508-43-6 |
Molecular Formula: | C23H26 O4 |
Molecular Weight: | 366.45 |
InChI: | InChI=1/C23H26O4/c1-22(2)9-14(24)20(15(25)10-22)19-13-7-5-6-8-17(13)27-18-12-23(3,4)11-16(26)21(18)19/h5-8,19,24H,9-12H2,1-4H3/t19-/m1/s1 |
Molecular Structure: |
|
Properties |
Flash Point: | 173°C |
Boiling Point: | 506.7°C at 760 mmHg |
Density: | 1.23g/cm3 |
Refractive index: | 1.603 |
Biological Activity: | Potent, selective non-peptide neuropeptide Y Y 5 receptor antagonist (K i = 26 nM for hY 5 ). Displays > 300-fold selectivity over hY 1 , hY 2 , and hY 4 receptors. Causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure. Centrally active upon oral administration in vivo . |
Flash Point: | 173°C |
Safety Data |
|
|