| Identification |
| CAS: | 674289-55-5 |
| Molecular Formula: | C18H16N2O2 |
| Molecular Weight: | 292.33184 |
| InChI: | InChI=1/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3 |
| Molecular Structure: |
![(C18H16N2O2) 3a-hydroxy-6-methyl-1-phenyl-1H,2H,3H,3aH,4H-pyrrolo[2,3-b]quinolin-4-one;4H-Pyrrolo[2,3-b]quinolin-...](https://img.guidechem.com/structure/674289-55-5.gif) |
| Properties |
| Density: | 1.312g/cm3 |
| Refractive index: | 1.681 |
| Appearance: | Bright Yellow Solid |
| Biological Activity: | Selective inhibitor of myosin II ATPase activity; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells. |
| Usage: | Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. It blocks both blebbing and cytokinesis at 50-100. A ne |
| Safety Data |
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