| Identification | |
| Name: | 19-Norpregn-4-en-20-yn-3-one,17-hydroxy-, (17a)- |
| Synonyms: | 19-Norethisterone;17a-Ethynyl-19-nortestosterone;17-Hydroxy-19-nor-17a-pregn-4-en-20-yn-3-one; |
| CAS: | 68-22-4 |
| EINECS: | 200-681-6 |
| Molecular Formula: | C20H26O2 |
| Molecular Weight: | 298.41924 |
| InChI: | InChI=1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,15-18,22H,4-11H2,2H3/t15-,16+,17+,18-,19-,20-/m0/s1 |
| Molecular Structure: |  |
| Properties | |
| Density: | 1.15 g/cm3 |
| Refractive index: | 1.577 |
| Appearance: | Off-White to Pale Yellow Solid |
| Report: | NTP 10th Report on Carcinogens. IARC Cancer Review: Animal Sufficient Evidence IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 294.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. Safety Profile
Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Mildly toxic by ingestion. Human systemic effects by ingestion: dermatitis and androgenic effects. Human teratogenic effects: developmental abnormalities of the musculoskeletal system and urogenital system; and behavioral effects in the newborn. Human reproductive effects: spermatogenesis; testes, epididymis, sperm duct changes; impotence; male breast development; other male effects; ovaries, fallopian tube changes; menstrual cycle changes or disorders; uterus, cervix, vagina effects; postpartum effects; changes in female fertility. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. |
| Color: | white to off-white |
| Usage: | Progesteron. Norethindrone and acetate in combination with estrogen as contraceptive (oral). It is reasonably anticipated to be a human carcinogen |
| Safety Data | |
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