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2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE (70006-24-5)

Identification
Name:2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE
Synonyms:ABT 724 TRIHYDROCHLORIDE;2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE
CAS:70006-24-5
Molecular Formula: C17H22Cl3N5
Molecular Weight: 402.74908
InChI: InChI=1/C17H19N5/c1-2-6-15-14(5-1)19-16(20-15)13-21-9-11-22(12-10-21)17-7-3-4-8-18-17/h1-8H,9-13H2,(H,19,20)
Molecular Structure: (C17H22Cl3N5) ABT 724 TRIHYDROCHLORIDE;2-[[4-(2-PYRIDINYL)-1-PIPERAZINYL]METHYL]-1H-BENZIMIDAZOLE TRIHYDROCHLORIDE
Properties
Flash Point: 285.6°C
Boiling Point: 548.6°C at 760 mmHg
Density:1.275g/cm3
Refractive index:1.687
Biological Activity: Potent dopamine D 4 receptor partial agonist (EC 50 = 12.4 nM; 61% efficacy vs. dopamine). Has no agonist activity at D 2 receptors (EC 50 > 10 μ M). Selective in rats in vivo : produces penile erection following i.c.v. administration; increases intracavernosal pressure and potentiates the proerectile effects of sildenafil following s.c. administration. Displays minimal side effects.
Flash Point: 285.6°C
Safety Data
 

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