Acetamide,2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy- (704888-90-4)

Identification
Name:	Acetamide,2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-
Synonyms:	ARP100
CAS:	704888-90-4
Molecular Formula:	C17H20 N2 O5 S
Molecular Weight:	0
Molecular Structure:
Properties
Biological Activity:	Selective inhibitor of MMP-2 (IC 50 = 12 nM); displays selectivity over MMP-9, MMP-3, MMP-1 and MMP-7 (IC 50 values are 200, 4500, > 50000 and > 50000 nM respectively). Exhibits anti-invasive properties in HT1080 fibrosarcoma cells.
Safety Data

Other Product

(2R)-2-[([1,1μ-Biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-3-methyl-butanamide, (R)-N-Hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
2-Pyrrolidinone,1-([1,1'-biphenyl]-4-ylsulfonyl)-5-(1-methylethoxy)-
Piperazine,1-[4-amino-6,7-bis(1-methylethoxy)-2-quinazolinyl]-4-([1,1'-biphenyl]-4-ylsulfonyl)-, monohydrochloride
5-Pyrimidinecarboxamide,2-[4-[[([1,1'-biphenyl]-4-ylsulfonyl)amino]methyl]-1-piperidinyl]-N-hydroxy-
5-Pyrimidinecarboxamide,2-[[1-([1,1'-biphenyl]-4-ylsulfonyl)-4-piperidinyl]amino]-N-hydroxy-
Benzamide,4-[4-[([1,1'-biphenyl]-4-ylsulfonyl)amino]-1-piperidinyl]-N-hydroxy-3-methyl-
Benzamide,4-[4-[([1,1'-biphenyl]-4-ylsulfonyl)amino]-1-piperidinyl]-N-hydroxy-
3-Pyridinecarboxamide,6-[4-[([1,1'-biphenyl]-4-ylsulfonyl)amino]-1-piperidinyl]-N-hydroxy-
3-Pyridinecarboxamide,6-[4-[[([1,1'-biphenyl]-4-ylsulfonyl)amino]methyl]-1-piperidinyl]-N-hydroxy-
3-Pyridinecarboxamide,6-[[1-([1,1'-biphenyl]-4-ylsulfonyl)-4-piperidinyl]amino]-N-hydroxy-
3-Pyridinecarboxamide,6-[3-[([1,1'-biphenyl]-4-ylsulfonyl)amino]-1-pyrrolidinyl]-N-hydroxy-
N-[4-(aziridin-1-ylsulfonyl)phenyl]acetamide
N-[4-(azepan-1-ylsulfonyl)phenyl]-2-(4-methoxyphenyl)acetamide
N-[4-(prop-2-en-1-ylsulfonyl)phenyl]acetamide
Piperidine, 1-[3-[[([1,1'-biphenyl]-4-ylsulfonyl)amino]methyl]benzoyl]-
Pyrrolidine, 1-[3-[[([1,1'-biphenyl]-4-ylsulfonyl)amino]methyl]benzoyl]-
N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]biphenyl-4-carboxamide
N-[4-(azepan-1-ylsulfonyl)phenyl]biphenyl-4-carboxamide
L-Leucine,N-[(1S)-3-[([1,1'-biphenyl]-4-ylsulfonyl)amino]-1-carboxypropyl]-
Piperazine,1-[4-amino-6,7-bis(2-propenyloxy)-2-quinazolinyl]-4-([1,1'-biphenyl]-4-ylsulfonyl)-, monohydrochloride