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Morpholine,2-[(R)-(2-ethoxyphenoxy)phenylmethyl]-, (2R)-rel- (71620-89-8)

Identification
Name:Morpholine,2-[(R)-(2-ethoxyphenoxy)phenylmethyl]-, (2R)-rel-
Synonyms:Reboxetine;Reboxitine;
CAS:71620-89-8
Molecular Formula: C19H23NO3
Molecular Weight: 313.39
Molecular Structure: (C19H23NO3) Reboxetine;Reboxitine;
Properties
Melting Point: 141-143ºC
Density:1.113 g/cm3
Water Solubility:Soluble to 50 mM in Water
Solubility:Soluble to 50 mM in Water
Appearance:White Solid
Biological Activity: Potent and selective inhibitor of noradrenalin uptake (K i values are 1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively). Displays > 1000-fold selectivity over α -adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active, clinically used antidepressant.
Safety Data