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2-Furancarboxylic acid,4,5-dihydro-5-methyl-4-oxo-5-phenyl- (72420-38-3)

Identification
Name:2-Furancarboxylic acid,4,5-dihydro-5-methyl-4-oxo-5-phenyl-
CAS:72420-38-3
Molecular Formula: C12H10O4
Molecular Weight: 218.2054
InChI: InChI=1/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)
Molecular Structure: (C12H10O4) (?à)-Acifran;AY 25712;Acifran;Reductol;
Properties
Density:1.343 g/cm3
Refractive index:1.591
Biological Activity: Hypolipidaemic agent; more potent than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC 50 values are 1.3? and 4.2 μ M respectively). In vivo, reduces serum triglycerides and circulating LDL-cholesterol without affecting liver weight or liver enzymes.
Safety Data
 

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