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1,2,8-Indolizinetriol,octahydro-, (1S,2R,8R,8aR)- (72741-87-8)

Identification
Name:1,2,8-Indolizinetriol,octahydro-, (1S,2R,8R,8aR)-
Synonyms:1,2,8-Indolizinetriol,octahydro-, [1S-(1a,2a,8b,8ab)]-;(-)-Swainsonine;D-Swainsonine;Swainsonine;Tridolgosir;(1S,2R,8R,8aR)-octahydroindolizine-1,2,8-triol;(1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol;1,2,8-Indolizinetriol, octahydro-, (1S,2R,8R,8aR)-;
CAS:72741-87-8
Molecular Formula: C8H15NO3
Molecular Weight: 173.2096
InChI: InChI=1/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6?,7-,8?/m1/s1
Molecular Structure: (C8H15NO3) 1,2,8-Indolizinetriol,octahydro-, [1S-(1a,2a,8b,8ab)]-;(-)-Swainsonine;D-Swainsonine;Swainsonine;Tri...
Properties
Density:1.38 g/cm3
Refractive index:1.608
Appearance:lyophilized powder
Biological Activity: Inhibitor of α -mannosidase II which inhibits glycoprotein processing. Displays anticancer and immune modulatory properties.
Storage Temperature: 2-8°C
Usage:Swainsonine is a plant alkaloid derived from Swainsona canescens (a leguminous plant). It is a reversible, active-site directed inhibitor of a-mannosidase at concentrations of 5-10mM. At acid pH, swainsonine resembles an intermediate in the hydroly
Safety Data
Hazard Symbols Xn: Harmful
 

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