| Identification |
| Name: | Adenosine, cyclic3',5'-[hydrogen [P(R)]-phosphorothioate] |
| Synonyms: | Adenosine,cyclic 3',5'-(hydrogen phosphorothioate), (R)-;4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv. |
| CAS: | 73208-40-9 |
| Molecular Formula: | C10H12 N5 O5 P S |
| Molecular Weight: | 446.46 |
| InChI: | InChI=1/C10H13N5O5PS/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7/h2-4,6-7,10,16-17,22H,1H2,(H2,11,12,13)/q+1/t4-,6-,7-,10-,21?/m1/s1 |
| Molecular Structure: |
![(C10H12N5O5PS) Adenosine,cyclic 3',5'-(hydrogen phosphorothioate), (R)-;4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adeno...](https://img1.guidechem.com/chem/e/dict/2/73208-40-9.jpg) |
| Properties |
| Biological Activity: | Cell-permeable cAMP analog; acts as a competitive antagonist of cAMP-induced activation of PKA (IC 50 = 11-16 μ M) by interacting with cAMP binding sites on the regulatory subunits. Resistant to hydrolysis by phosphodiesterases. Also available as part of the PKA Tocriset™ . |
| Storage Temperature: | −20°C |
| Color: | white |
| Safety Data |
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