Identification |
Name: | Benzamide,3-bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2,6-dimethoxy-, hydrochloride(1:1) |
Synonyms: | Benzamide,3-bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2,6-dimethoxy-, monohydrochloride,(S)-;Benzamide,3-bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2,6-dimethoxy-,monohydrochloride (9CI);(-)-FLA 731;A 33547;A 33547 hydrochloride;FLA 731;FLA 731, (-)-;Remoxipride hydrochloride;Roxiam; |
CAS: | 73220-03-8 |
Molecular Formula: | C16H23 Br N2 O3 . Cl H |
Molecular Weight: | 407.73 |
InChI: | InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 |
Molecular Structure: |
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Properties |
Specification: | usageEng:Specific dopamine D2-receptor antagonist. Antipsychotic. |
Biological Activity: | Standard D 2 receptor antagonist showing some selectivity over D 3 and D 4 receptors (K i values are ~ 300, ~ 1600, and ~ 2800 nM for D 2 , D 3 and D 4 receptors respectively). In vivo remoxipride is an antipsychotic which does not cause extrapyramidal side effects and is 50-fold more potent than sulpiride in antagonising the effects of apomorphine in the rat. |
Storage Temperature: | Store at RT |
Usage: | Specific dopamine D2-receptor antagonist. Antipsychotic. |
Safety Data |
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