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Cilostazol (73963-72-1)

Identification
Name:Cilostazol
Synonyms:6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one;Pletal;OPC 13013;Cilostazol (JAN/USAN);2(1H)-Quinolinone,6-[4-(1-cyclohexyl-1Htetrazol- 5-yl)butoxy]-3,4-dihydro-;Pletal (TN);Cilostazole;Cilostal;
CAS:73963-72-1
Molecular Formula: C20H27N5O2
Molecular Weight: 369.52
Molecular Structure: (C20H27N5O2) 6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one;Pletal;OPC 13013;Cilostazol (J...
Properties
Density:1.34 g/cm3
Refractive index:1.675
Water Solubility:DMSO: 18 mg/mL, soluble
Solubility:DMSO: 18 mg/mL, soluble
Appearance:off-white solid
Specification:

? Cilostazol , with CAS number of 73963-72-1, can be called 3,4-Dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-
2(1H)-quinolinone ; 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone ; 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril ; Pletal ; Cilostazolum . It is an?off-white solid,?Cilostazol (CAS NO.73963-72-1) is a medication used in the alleviation of the symptom of intermittent claudication in individuals with peripheral vascular disease. Besides cilostazol is a selective PDE3 phosphodiesterase inhibitor with therapeutic focus on cAMP. It inhibits platelet aggregation and is a direct arterial vasodilator. Its main effects are dilation of the arteries supplying blood to the legs and decreasing platelet coagulation.

Storage Temperature: Store in original container in a cool dark place.
Color: off-white
Usage:

A potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo

Safety Data
Hazard Symbols Xi: Irritant