Specification: |
The Nickel, with the cas registry number 7440-02-0, has the systematic name of nickel(2+). For being a kind of silver white, hard, malleable metal chunks or grey powder, it is stable in massive form and may react violently with titanium, ammonium nitrate, potassium perchlorate, hydrazoic acid. Besides, it is incompatible with acids, oxidizing agents, sulfur.
The characteristics of this chemical are as follows: (1)#H bond acceptors: 0; (2)#H bond donors: 0; (3)#Freely Rotating Bonds: 0; (4)Polar Surface Area: 0; (5)Exact Mass: 57.935348; (6)MonoIsotopic Mass: 57.935348; (7)Heavy Atom Count: 1; (8)Covalently-Bonded Unit Count: 1.
As to its usage, it is used widely to make coins and nickel steel for armor plates and a component in Nichrome(R), and is also used as the burglar-proof vaultsPermalloy(R)?and constantan. Besides, it is extensively used for making stainless steel and other corrosion-resistant alloys, such as Inconel(R),Invar(R),and the Hastelloys(R).
When you are dealing with this chemical, you should be very cautious. For one thing, it is irritant which may cause inflammation to the skin or other mucous membranes and may cause sensitization by skin contact. For another thing, it is harmful which may cause damage to health and may have limited evidence of a carcinogenic effect. In addition, it is corrosive which may destroy living tissue on contact and it may causes burns. Beside all these, it is highly flammable which may catch fire in contact with air, only needing brief contact with an ignition source, and it has a very low flash point or evolve highly flammable gases in contact with water. Then for being very toxic to aquatic organisms, it may cause long-term adverse effects in the aquatic environment.
Therefore, you should take different measures to deal with different cases. First important thing is to wear suitable protective clothing and gloves. And if in case of contact with eyes, rinse immediately with plenty of water and seek medical advice and if in case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) When comes to its storage, keep it away from sources of ignition and heat. Then remember that this material and its container must be disposed of as hazardous waste. What's more, avoid releasing to the environment and you could also refer to special instructions / safety data sheets.
In addition, you could convert the following datas into the molecular structure:
(1)Canonical SMILES: [Ni]
(2)InChI: InChI=1S/Ni
(3)InChIKey: PXHVJJICTQNCMI-UHFFFAOYSA-N?
Below are the toxicity information of this chemical:
Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
cat |
LDLo |
subcutaneous |
12500ug/kg (12.5mg/kg) |
? |
National Technical Information Service. Vol. PB158-508, |
guinea pig |
LDLo |
oral |
5mg/kg (5mg/kg) |
? |
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 455, 1980. |
mouse |
LDLo |
intravenous |
50mg/kg (50mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: FLUID INTAKE
KIDNEY, URETER, AND BLADDER: PROTEINURIS |
Farmakologiya i Toksikologiya Vol. 23, Pg. 549, 1960.
? |
rabbit |
LDLo |
intraperitoneal |
7mg/kg (7mg/kg) |
? |
National Technical Information Service. Vol. PB158-508, |
rabbit |
LDLo |
subcutaneous |
7500ug/kg (7.5mg/kg) |
? |
National Technical Information Service. Vol. PB158-508, |
rat |
LD50 |
intraperitoneal |
250mg/kg (250mg/kg) |
VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION
LIVER: OTHER CHANGES
BLOOD: OTHER CHANGES |
Industrial Medicine. Vol. 15, Pg. 482, 1946. |
rat |
LDLo |
intratracheal |
12mg/kg (12mg/kg) |
? |
National Technical Information Service. Vol. AEC-TR-6710, |
rat |
LDLo |
oral |
5gm/kg (5000mg/kg) |
? |
Food & Drug Research Laboratories, Inc., Papers. Vol. 7684D, Pg. 1983, |
|
Report: |
NTP 10th Report on Carcinogens. IARC Cancer Review: Group 1 IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 264.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 11 ,1976,p. 75.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 2 ,1973,p. 126.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Community Right-To-Know List. Reported in EPA TSCA Inventory.
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