Benzamide,5-chloro-2-methoxy-4-(methylamino)-N-[(2R,3R)-2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]-,rel- (75272-39-8)

Identification
Name:	Benzamide,5-chloro-2-methoxy-4-(methylamino)-N-[(2R,3R)-2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]-,rel-
Synonyms:	Benzamide,5-chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]-,cis-; Emilace; Emonapride; Nemonapride; YM 09151; YM 09151-2
CAS:	75272-39-8
Molecular Formula:	C21H26 Cl N3 O2
Molecular Weight:	387.9
InChI:	InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m1/s1
Molecular Structure:
Properties
Specification:	Colourless Crystalline Solid usageEng:A selective dopamine D2 receptor antagonist. Used as an antipsychotic
Biological Activity:	Highly potent dopamine D 2 -like receptor antagonist; selective over D 1 -like receptors (K i values are 0.1 and 740 nM for D 2 -like and D 1 -like receptors respectively). Also potent 5-HT 1A receptor agonist (IC 50 = 34 nM) and has affinity for sigma receptors.
Storage Temperature:	Store at RT
Usage:	A selective dopamine D2 receptor antagonist. Used as an antipsychotic
Safety Data