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Cautions:?Moxonidine (CAS NO.75438-57-2)?should not be used for treatment in?patients with moderate to severe renal impairment. Abrupt discontinuation of the drug should also be avoided. If concomitant treatment with a beta blocker has to be stopped, the beta blocker should be discontinued first, then moxonidine after a few days.
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Drug interactions: It?is not indicated that concomitant administration of moxonidine and a thiazide diuretic such as hydrochlorothiazide, as both drugs' hypotensive effects may be enhanced.
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Side-effects: Noteworthy side effects?are as follows:?dry mouth, headache, fatigue, dizziness, nausea, sleep disturbances (rarely sedation), asthenia, vasodilatation, and rarely, skin reactions.
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