9H-Carbazole,9-[3-[(3R,5S)-3,5-dimethyl-1-piperazinyl]propyl]-, hydrochloride (1:2), rel- (75859-03-9)

Identification
Name:	9H-Carbazole,9-[3-[(3R,5S)-3,5-dimethyl-1-piperazinyl]propyl]-, hydrochloride (1:2), rel-
Synonyms:	9H-Carbazole,9-[3-(3,5-dimethyl-1-piperazinyl)propyl]-, dihydrochloride, cis-; 9H-Carbazole,9-[3-[(3R,5S)-3,5-dimethyl-1-piperazinyl]propyl]-, dihydrochloride, rel- (9CI);BW 234U; Rimcazole dihydrochloride; Rimcazole hydrochloride
CAS:	75859-03-9
Molecular Formula:	C21H27 N3 . 2 Cl H
Molecular Weight:	394.38
InChI:	InChI=1/C21H27N3.2ClH/c1-16-14-23(15-17(2)22-16)12-7-13-24-20-10-5-3-8-18(20)19-9-4-6-11-21(19)24;;/h3-6,8-11,16-17,22H,7,12-15H2,1-2H3;2*1H/t16-,17+;;
Molecular Structure:
Properties
Flash Point:	255.7°C
Boiling Point:	499.1°C at 760 mmHg
Biological Activity:	Antagonist at σ receptors (IC 50 values are 1480 and 386 nM at σ 1 and σ 2 receptors respectively). Also binds to the dopamine transporter (IC 50 = 57.6 nM) and inhibits dopamine uptake. Reduces the stimulatory effects of cocaine in vivo .
Flash Point:	255.7°C
Safety Data