| Identification | |
| Name: | (-)-MK 801 Maleate |
| Synonyms: | 5H-Dibenzo(a,d)cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (+)-, (Z)-2-butenedioate (1:1);5H-Dibenzo[a,d]cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S)-, (2Z)-2-butenedioate (1:1);Dizocilpina [INN-Spanish];Dizocilpinum [INN-Latin];(+)-10,11-Dihydro-5-methyl-5H-dibenzo(a,d)cyclohepten-5,10-diyldiammonium maleate;MK 801;Dizocilpine maleate;Dizocilpine maleate [USAN];5H-Dibenzo(a,d)cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S)-;77086-21-6;5H-Dibenzo[a,d]cyclohepten-5,10-imine,10,11- dihydro-5-methyl-,(5S)-,(2Z)-2-butenedioate (1:1);MK-801;Prestwick_903;(+)-10,11-Dihydro-5-methyl-5H-dibenzo(a,d)cyclohepten-5,10-imine maleate (1:1);(+)-MK-801 MALEATE;(5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate;(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (Z)-2-Butenedioate (1:1);(1S,9R)-1-Methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2,4,6,10,12,14-hexaene (2Z)-but-2-enedioate (1:1);(5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene (2Z)-but-2-enedioate (1:1);5H-Dibenzo[a,d]cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S,10R)-, (2Z)-2-butenedioate (1:1);Neurogard; |
| CAS: | 77086-22-7 |
| EINECS: | 278-614-5 |
| Molecular Formula: | C20H19NO4 |
| Molecular Weight: | 440.454 |
| InChI: | InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29) |
| Molecular Structure: |  |
| Properties | |
| Melting Point: | 183-185 deg C |
| Flash Point: | 281°C |
| Boiling Point: | 541°C at 760 mmHg |
| Water Solubility: | DMSO: >20 mg/mL |
| Solubility: | In water, 1.4X10-1 mg/L at 25 deg C (est) |
| Appearance: | White Solid |
| Specification: | Safety Statements:22-24/25 22:Do not breathe dust 24/25:Avoid contact with skin and eyes |
| Biological Activity: | A potent, selective and non-competitive NMDA receptor antagonist. Acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca 2+ flux. An effective anti-ischemic agent in several animal models. Also available as part of the Mixed NMDA Receptor Tocriset™ . |
| Flash Point: | 281°C |
| Storage Temperature: | Store at RT |
| Color: | white |
| Safety Data | |
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