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Cyclosporin H (83602-39-5)

Identification
Name:Cyclosporin H
Synonyms:Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl];Sandoz 37-839;CyclosporinA, 5-(N-methyl-D-valine)-;
CAS:83602-39-5
Molecular Formula: C62H111N11O12
Molecular Weight: 1216.6378
InChI: InChI=1/C63H113N11O12/c1-26-28-29-41(15)53(76)52-56(79)66-44(27-2)58(81)67(18)34-49(75)68(19)46(31-36(5)6)60(83)72(23)50(39(11)12)62(85)69(20)45(30-35(3)4)55(78)64-42(16)54(77)65-43(17)57(80)70(21)47(32-37(7)8)59(82)71(22)48(33-38(9)10)61(84)73(24)51(40(13)14)63(86)74(52)25/h26,28,35-48,50-53,76H,27,29-34H2,1-25H3,(H,64,78)(H,65,77)(H,66,79)/b28-26+/t41-,42+,43-,44+,45+,46+,47-,48+,50-,51+,52?,53-/m1/s1
Molecular Structure: (C62H111N11O12) Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valyl-(3R,4R,6E)-6,7-didehydr...
Properties
Melting Point: 162-165 oC
Density:1.015 g/cm3
Refractive index:1.468
Water Solubility:insoluble in water
Solubility:Soluble in 100% ethanol, acetone or ethyl acetate; insoluble in water
Appearance:White crystalline power
Specification:
White Powder
usageEng:An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
Usage:

 Cyclosporin H (83602-39-5) is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Safety Data