2H-Naphtho[2,1-c]pyran-7-carboxylicacid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-,methyl ester, (2S,4aR,6aR,7R,9S,10aS,10bR)- (83729-01-5)

Identification
Name:	2H-Naphtho[2,1-c]pyran-7-carboxylicacid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-,methyl ester, (2S,4aR,6aR,7R,9S,10aS,10bR)-
Synonyms:	2H-Naphtho[2,1-c]pyran-7-carboxylicacid, 9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-,methyl ester, [2S-(2a,4aa,6ab,7b,9b,10aa,10bb)]-; (-)-Salvinorin A; Divinorin A; Salvinorin; Salvinorin A
CAS:	83729-01-5
Molecular Formula:	C23H28 O8
Molecular Weight:	432.47
InChI:	InChI=1/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1
Molecular Structure:
Properties
Melting Point:	238-240 deg C; also reported as 242-244 deg C
Flash Point:	294.8°C
Boiling Point:	563.8°C at 760 mmHg
Density:	1.28g/cm³
Refractive index:	1.547
Solubility:	In water, 25.07 mg/L at 25 deg C (est)
Biological Activity:	Potent naturally occuring non-nitrogenous κ -opioid selective agonist that displays high affinity at both native (K i = 4.3 nM) and cloned (K i = 16 nM) κ -opioid receptors. Also exhibits allosteric modulation of μ -opioid receptor binding. Reported to be brain-penetrant and displays psychoactive properties.
Flash Point:	294.8°C
Storage Temperature:	−20°C
Color:	Colorless crystals from methanol
Safety Data