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Azithromycin (83905-01-5)

Identification
Name:Azithromycin
Synonyms:Azithromycin [USAN:BAN:INN];Misultina;1-Oxa-6-azacyclopentadecan-15-one,13-[(2,- 6-dideoxy-3-C-methyl-3-O-methyl-R-Lribo- hexopyranosyl)oxy]-2-ethyl-3,4,10- trihydroxy-3,5,6,8,10,12,14-heptamethyl-11- [[3,4,6-trideoxy-3-(dimethylamino)-a-D-xylohexopyranosyl] oxy]-,(2R,3S,4R,5R,8R,10R,11R,- 12S,13S,14R)-;Azithromycin (AIDS Initiative);Hemomycin;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one;9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A;Zithromax;Tobil;Zitrotek;Aritromicina [Spanish];(2R,3R,4R,5R,8R,10R,11R,13S,14R)-11-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one;Azitromax;Azithromycinum [Latin];CP-62993;Setron;Sumamed;Azithromycine [French];Zeto;Zitromax;Aztrin;Zithrax;1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methylhexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-;Zifin;[2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-;Azithromycin? /Azithromycin Dihydrate;Azithromycin Dihydrate;Azithromycin(water soluble);
CAS:83905-01-5
Molecular Formula: C38H72N2O12
Molecular Weight: 748.99
InChI: InChI=1/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22?,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
Molecular Structure: (C38H72N2O12) Azithromycin [USAN:BAN:INN];Misultina;1-Oxa-6-azacyclopentadecan-15-one,13-[(2,- 6-dideoxy-3-C-methy...
Properties
Density:1.18 g/cm3
Stability:Stable. Incompatible with strong oxidizing agents.
Refractive index:1.536
Solubility:Insoluble
Appearance:white crystalline powder
Specification:

? Azithromycin ,?its cas register number is 83905-01-5. It also can be called?(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one ; 9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A ; Aritromicina ; Azasite ; Azenil ; Azitrocin ; Azitromax ; Aztrin ;
?Hemomycin ; Misultina ; Mixoterin ; Setron ; Sumamed ; Tobil ; Tromix ; Trulimax ; Zithrax ; Zithromax .
?

Biological Activity: Macrolide antibiotic. Inhibits 50S ribosomal subunit formation and elongation at transpeptidation step in gram-positive and gram-negative organisms. Orally active with improved pharmacokinetics over erythromycin in mouse models.
Color: Crystals
Usage:

Semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial

Safety Data
Hazard Symbols Xi: Irritant
 

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