Identification |
Name: | 1H-Isoindole-1,3(2H)-dione,2-[(3S)-2,6-dioxo-3-piperidinyl]- |
Synonyms: | 1H-Isoindole-1,3(2H)-dione,2-(2,6-dioxo-3-piperidinyl)-, (S)-;Phthalimide, N-(2,6-dioxo-3-piperidyl)-,L-(-)- (8CI);(-)-Thalidomide;(S)-(-)-Thalidomide;(S)-Thalidomide;NSC 91730;S-(L)-Thalidomide;Thalidomide, L-; |
CAS: | 841-67-8 |
EINECS: | 200-031-1 |
Molecular Formula: | C13H10N2O4 |
Molecular Weight: | 258.25 |
InChI: | InChI=1/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)/t9-/m0/s1 |
Molecular Structure: |
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Properties |
Transport: | UN 2811 6.1/PG 2 |
Flash Point: | 262.1°C |
Boiling Point: | 509.7°C at 760 mmHg |
Density: | 1.503g/cm3 |
Refractive index: | 1.646 |
Solubility: | Sparingly soluble in methanol, ethanol, acetone, ethyl acetate, butyl acetate, glacial acetic acid. Very soluble in dioxane, DMF, pyridine. Practically insoluble in ether, chloroform, benzene. In water, 45-60 mg/l @ 25 deg C. |
Appearance: | Needles |
Flash Point: | 262.1°C |
Color: | white |
Usage: | Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative |
Safety Data |
Hazard Symbols |
T: Toxic
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