| Identification |
| Name: | Y 134 |
| Synonyms: | [6-HYDROXY-2-(4-HYDROXYPHENYL)BENZO[B]THIEN-3-YL]-[4-[4-(1-METHYLETHYL)-1-PIPERAZINYL]PHENYL]METHANONE;Y 134 |
| CAS: | 849662-80-2 |
| Molecular Formula: | C28H28N2O3S |
| Molecular Weight: | 0 |
| InChI: | InChI=1/C28H28N2O3S/c1-18(2)29-13-15-30(16-14-29)21-7-3-19(4-8-21)27(33)26-24-12-11-23(32)17-25(24)34-28(26)20-5-9-22(31)10-6-20/h3-12,17-18,31-32H,13-16H2,1-2H3 |
| Molecular Structure: |
![(C28H28N2O3S) [6-HYDROXY-2-(4-HYDROXYPHENYL)BENZO[B]THIEN-3-YL]-[4-[4-(1-METHYLETHYL)-1-PIPERAZINYL]PHENYL]METHANO...](https://img.guidechem.com/structure/849662-80-2.gif) |
| Properties |
| Flash Point: | 390.623°C |
| Boiling Point: | 722.282°C at 760 mmHg |
| Density: | 1.282g/cm3 |
| Refractive index: | 1.673 |
| Biological Activity: | Selective estrogen receptor modulator (SERM) that displays selectivity for ER α over ER β (K i values are 0.09 and 11.31 nM respectively) and no cross-reactivity with mineralocorticoid, glucocorticoid, androgen and progesterone receptors. Acts as an agonist in the bone and antagonist in reproductive tissue. Suppresses estrogen-stimulated proliferation of ER-positive human breast cancer MCF-7 and T47D cells. |
| Flash Point: | 390.623°C |
| Storage Temperature: | Desiccate at RT |
| Safety Data |
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