4H-Pyrrolo[2,3-b]quinolin-4-one,1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aS)- (856925-71-8)

Identification
Name:	4H-Pyrrolo[2,3-b]quinolin-4-one,1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aS)-
Synonyms:	(-)-Blebbistatin
CAS:	856925-71-8
Molecular Formula:	C18H16 N2 O2
Molecular Weight:	0
Molecular Structure:
Properties
Biological Activity:	Selective inhibitor of myosin II ATPase activity (IC 50 ~0.5-5 μ M); active enantiomer of (±)-blebbistatin ((?-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one ). Inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells.
Safety Data

Other Product

4H-Pyrrolo[2,3-b]quinolin-4-one,1,2,3,3a-tetrahydro-3a-hydroxy-7-nitro-1-phenyl-, (3aS)-
Pyrrolo[2,3-b]indol-2(1H)-one,6-bromo-3,3a,8,8a-tetrahydro-1-methyl-3a,8-bis(3-methyl-2-buten-1-yl)-,(3aS,8aS)-
2-Cyclopenten-1-one,3-[(3aS,8aR)-3a,8a-dihydro-4-hydroxy-6-methoxyfuro[2,3-b]benzofuran-5-yl]-
2-Cyclopenten-1-one, 3-((3aS,8aR)-3a,8a-dihydro-4-hydroxy-6-methoxyfuro(2,3-b)benzofuran-5-yl)-
Pyrrolo[2,3-b]indole,6-bromo-1,2,3,3a,8,8a-hexahydro-1-methyl-3a-(3-methyl-2-butenyl)-, (3aS-cis)-(9CI)
Ethanone, 1-[(3aS,6aS)-3a,6a-dihydro-2-methyl-4H-cyclopenta[b]furan-3-yl]-
4H-Pyrrolo[2,3-b]quinolin-4-one,1,2,3,9-tetrahydro-6-methyl-1-phenyl-
3-[(3aS,8aR)-4-hydroxy-6-methoxy-3a,8a-dihydrofuro[2,3-b][1]benzofuran-5-yl]cyclopent-2-en-1-one
2(3H)-Benzofuranone,3a,4,7,7a-tetrahydro-4- hydroxy-5-[(1S)-4-hydroxy-1-methylbutyl]- 6-methyl-3-methylene-,(3aS,4S,7aR)-
6(2H)-Benzofuranone,3,3a,7,7a-tetrahydro-2-(4-hydroxy-3-methoxyphenyl)-3a,7a-dimethoxy-3-methyl-5-(2-propen-1-yl)-,(2S,3R,3aS,7aR)-
Pyrrolo[2,3-b]indole,6-bromo-1,2,3,3a,8,8a-hexahydro-1-methyl-3a,8-bis(3-methyl-2-buten-1-yl)-,(3aS,8aR)-
2(3H)-Benzofuranone,5-[(1S)-4-(acetyloxy)-1-methylbutyl]-3a,4,7,7a-tetrahydro-4-hydroxy-6-methyl-3-methylene-,(3aS,4S,7aR)-
(3aS,7aR)-5,7-dibromo-3a-hydroxy-6-methoxy-3a,7a-dihydro-1-benzofuran-2(3H)-one
4H-Pyrrolo[2,3-b]quinolin-4-one,1,2,3,9-tetrahydro-1-methyl-9-(phenylmethyl)-, hydrochloride (1:2)
(2S,3R)-1-((3aS,6R,7aR)-8,8-dimethyl-2,2-dioxidotetrahydro-3H-3a,6-methanobenzo[c]isothiazol-1(4H)-yl)-3-hydroxy-2-methyl-5-(trimethylsilyl)pent-4-yn-1-one
4H-3a,7-Methanocycloocta[b]furan-8,10(5H)- dione,2,3,6,7-tetrahydro-2-(1-hydroxy-1- methylethyl)-6,6-dimethyl-5,9-bis(3-methyl- 2-butenyl)-7-(2-methyl-1-oxopropyl)-,(2S,- 3aS,5S,7R)-
4H,6H-3a,6a-Methanooxireno[e]isobenzofuran- 6-one,4-(3-furanyl)-6b-[[(2S,3'S,5'S)-2,2',- 3',4',5,5'-hexahydro-5'-hydroxy-2,2',2'- trimethyl-5-oxo[2,3'-bifuran]-5'-yl]methyl]- tetrahydro-,(1aS,3aS,4R,6aR,6bR)-
b-D-Allopyranoside,(3aS,4R,5R,6R,6aS)-2-(dimethylamino)-3a,5,6,6a-tetrahydro-5-hydroxy-6-[(phenylmethoxy)methyl]-4H-cyclopentoxazol-4-yl2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-
b-D-Allopyranoside,(3aS,4R,5R,6R,6aS)-2-(dimethylamino)-3a,5,6,6a-tetrahydro-5-hydroxy-6-[(phenylmethoxy)methyl]-4H-cyclopentoxazol-4-yl2-(acetylamino)-2-deoxy-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-
b-D-Allopyranoside,2-(dimethylamino)-3a,5,6,6a-tetrahydro-5-hydroxy-6-[(phenylmethoxy)methyl]-4H-cyclopentoxazol-4-yl2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-b-D-allopyranosyl]-2-deoxy-3,6-bis-O-(phenylmethyl)-,[1(3aS,4R,5R,6R,6aS),4(R)]- (9CI)