| Identification |
| Name: | 5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one,6,7,12,13-tetrahydro- |
| Synonyms: | AntibioticK 252c; K 252c; SD 1825; Staurosporine aglycon; Staurosporinone |
| CAS: | 85753-43-1 |
| Molecular Formula: | C20H13 N3 O |
| Molecular Weight: | 311.34 |
| Molecular Structure: |
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| Properties |
| Biological Activity: | Inhibitor of protein kinase C (IC 50 = 2.45 μ M) that displays ~ 10-fold selectivity over protein kinase A (IC 50 = 25.7 μ M). Also inhibits β -lactamase, malate dehydrogenase and chymotrypsin (IC 50 values are 8, 8 and 10 μ M respectively). Exhibits antiviral activity against GCV-sensitive and -resistant strains of human cytomegalovirus (HCMV) (IC 50 values range from 0.13-0.32 μ M). Shows no activity against herpes simplex virus (HSV). |
| Storage Temperature: | −20°C |
| Safety Data |
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